The first comprehensive coverage of this unique and interdisciplinary field provides a complete overview, covering such topics as chemoenzymatic synthesis, microbial production of DNA building blocks, asymmetric transformations by coupled enzymes and much more. By combining enzymatic and synthetic organic steps, the use of multi-enzyme complexes and other techniques opens the door to reactions hitherto unknown, making this monograph of great interest to biochemists, organic chemists, and chemists working with/on organometallics, as well as catalytic chemists, biotechnologists, and those working in the pharmaceutical and fine chemical industries.
Thứ Tư, 28 tháng 1, 2015
Biocatalysis - From Discovery to Application
Catalytic procedures are clearly the most economical means to effect selective processes in organic synthesis. For the preparation of enantiomerically pure compounds, the utilization of enzymes is particularly attractive because of high selectivities and mild, environmentally benign reaction conditions. Taking advantage of advances in molecular biology, unique new enzymes are now readily accessible in quantity with properties that are amenable to modification on demand. This volume brings together leading contributors from the forefront of this exciting technology. In their authoritative and timely rewies they cover the state-of-the-art of biocatalysis from the discovery of novel enzymes – by modern screening, evolutionary or immunological approaches – through immobilization techniques for technical processes, to their use in the asymmetric synthesis of important target compounds. Thus, several chapters illustrate the synthetic potential of recently emerging biocatalysts in the phospholipid, epoxide, cyanohydrin, and oligosaccharide fields.
Thứ Hai, 5 tháng 1, 2015
Biosensors Based on Aptamers and Enzymes
Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.
Thứ Bảy, 3 tháng 1, 2015
Bioanalytical Applications of Enzymes
Details the latest advances in bioanalytical applications using enzymes–techniques that are becoming increasingly important in analysis, synthesis, manufacturing and medical diagnosis. Consists of seven articles which cover: enzyme labeled antibodies in bioassays, DNA restriction enzymes and RFLPs in medicine, enzyme-labeled probes for nucleic acid hybridization, unique methodologies of immobilized proteins in bioanalytical systems, dry reagent chemistry fundamentals, the theory and applications of enzyme electrode biosenors, and advances in enzymatically coupled field effect transistors.