This book reports the text of the lectures of the 6th International Conference on Sodium Calcium Exchange held in Lacco Ameno in the Island of Ischia in the Gulf of Naples, Italy, from October 1 to October 5, 2011. The present book uncovers the most striking new findings on NCX that emerged since the previous Conference on Sodium Calcium Exchange, such as the structural dissection of the molecular determinants of Ca2+ sensitivity of the exchanger, the epigenetic regulation of ncx1 gene, the molecular identification of the mitochondrial Sodium Calcium Exchanger, and the discovery of NCX in unexpected anatomical locations such as the female reproductive tract.The book is organized into 11 parts covering NCX structural aspects, genetic and epigenetic regulation, regulatory mechanisms, subcellular localization in mitochondria, involvement in neurodegenerative diseases and in immune regulation, and the role of the cardiovascular and endocrine systems, as well as diabetes in physiology and pathophysiology. Selected chapters of the book are also devoted to the interaction of NCKX and other ion channels and transporters with NCX, like ASICs, TRPM, and NHE.
Thứ Hai, 20 tháng 4, 2015
Thứ Hai, 6 tháng 4, 2015
Visual Texture
This book surveys the state of the art in multidimensional, physically-correct visual texture modeling. Features: reviews the entire process of texture synthesis, including material appearance representation, measurement, analysis, compression, modeling, editing, visualization, and perceptual evaluation; explains the derivation of the most common representations of visual texture, discussing their properties, advantages, and limitations; describes a range of techniques for the measurement of visual texture, including BRDF, SVBRDF, BTF and BSSRDF; investigates the visualization of textural information, from texture mapping and mip-mapping to illumination- and view-dependent data interpolation; examines techniques for perceptual validation and analysis, covering both standard pixel-wise similarity measures and also methods of visual psychophysics; reviews the applications of visual textures, from visual scene analysis in medical applications, to high-quality visualizations in the automotive industry.
Chủ Nhật, 1 tháng 3, 2015
Clusters in Nuclei, Volume 1
Following the pioneering discovery of alpha clustering and of molecular resonances, the field of nuclear clustering is presently one of the domains of heavy-ion nuclear physics facing both the greatest challenges and opportunities. After many summer schools and workshops, in particular over the last decade, the community of nuclear molecular physics decided to team up in producing a comprehensive collection of lectures and tutorial reviews covering the field. This first volume, gathering seven extensive lectures, covers the follow topics: * Cluster Radioactivity * Cluster States and Mean Field Theories * Alpha Clustering and Alpha Condensates * Clustering in Neutron-rich Nuclei * Di-neutron Clustering * Collective Clusterization in Nuclei * Giant Nuclear Molecules By promoting new ideas and developments while retaining a pedagogical nature of presentation throughout, these lectures will both serve as a reference and as advanced teaching material for future courses and schools in the fields of nuclear physics and nuclear astrophysics.
Introduction to Thin Film Transistors
Introduction to Thin Film Transistors reviews the operation, application and technology of the main classes of thin film transistor (TFT) of current interest for large area electronics. The TFT materials covered include hydrogenated amorphous silicon (a-Si:H), poly-crystalline silicon (poly-Si), transparent amorphous oxide semiconductors (AOS), and organic semiconductors. The large scale manufacturing of a-Si:H TFTs forms the basis of the active matrix flat panel display industry. Poly-Si TFTs facilitate the integration of electronic circuits into portable active matrix liquid crystal displays, and are increasingly used in active matrix organic light emitting diode (AMOLED) displays for smart phones. The recently developed AOS TFTs are seen as an alternative option to poly-Si and a-Si:H for AMOLED TV and large AMLCD TV applications, respectively. The organic TFTs are regarded as a cost effective route into flexible electronics. As well as treating the highly divergent preparation and properties of these materials, the physics of the devices fabricated from them is also covered, with emphasis on performance features such as carrier mobility limitations, leakage currents and instability mechanisms. The thin film transistors implemented with these materials are the conventional, insulated gate field effect transistors, and a further chapter describes a new thin film transistor structure: the source gated transistor, SGT.The driving force behind much of the development of TFTs has been their application to AMLCDs, and there is a chapter dealing with the operation of these displays, as well as of AMOLED and electrophoretic displays. A discussion of TFT and pixel layout issues is also included.For students and new-comers to the field, introductory chapters deal with basic semiconductor surface physics, and with classical MOSFET operation. These topics are handled analytically, so that the underlying device physics is clearly revealed. These treatments are then used as a reference point, from which the impact of additional band-gap states on TFT behaviour can be readily appreciated.This reference book, covering all the major TFT technologies, will be of interest to a wide range of scientists and engineers in the large area electronics industry. It will also be a broad introduction for research students and other scientists entering the field, as well as providing an accessible and comprehensive overview for undergraduate and postgraduate teaching programmes.
Thứ Tư, 25 tháng 2, 2015
Clusters in Nuclei, Volume 3
Following the pioneering discovery of alpha clustering and of molecular resonances, the field of nuclear clustering is today one of those domains of heavy-ion nuclear physics that faces the greatest challenges, yet also contains the greatest opportunities. After many summer schools and workshops, in particular over the last decade, the community of nuclear molecular physicists has decided to collaborate in producing a comprehensive collection of lectures and tutorial reviews covering the field. This third volume follows the successful Lect. Notes Phys. 818 (Vol. 1) and 848 (Vol. 2), and comprises six extensive lectures covering the following topics:
Thermal Energy Storage
The ability of thermal energy storage (TES) systems to facilitate energy savings, renewable energy use and reduce environmental impact has led to a recent resurgence in their interest. The second edition of this book offers up-to-date coverage of recent energy efficient and sustainable technological methods and solutions, covering analysis, design and performance improvement as well as life-cycle costing and assessment. As well as having significantly revised the book for use as a graduate text, the authors address real-life technical and operational problems, enabling the reader to gain an understanding of the fundamental principles and practical applications of thermal energy storage technology.
Thứ Bảy, 21 tháng 2, 2015
Encyclopedia of Adolescence
The period of adolescence involves growth, adaptation, and dramatic reorganization in almost every aspect of social and psychological development. The Encyclopedia of Adolescence offers an exhaustive and comprehensive review of current theory and research findings pertaining to this critical decade of life. Leading scientists offer accessible and easily readable reviews of biological, social, educational, occupational, and cultural factors that shape adolescent development. Issues in normative development, individual differences, and psychopathology/maladjustment are reviewed. Over 130 chapters are included, each covering a specific aspect or issue of adolescence. The chapters trace differences in the course of adolescence in different nations and among youth with different backgrounds.
Thứ Hai, 9 tháng 2, 2015
The Internet For Dummies, Twelfth Edition
Don’t miss the 12th edition of this bestseller, fully updated and now covering social networking!
Chủ Nhật, 8 tháng 2, 2015
Pharmaceutics
Pharmaceutics: Basic Principles and Application to Pharmacy Practice is a valuable textbook covering the basic science as well as the role and application of pharmaceutics within pharmacy practice. Based on curricular guidelines mandated by the American Council for Pharmacy Education (ACPE), this book incorporates laboratory skills by identifying portions of each principle that can be used in a clinical setting. In this way, instructors are able to demonstrate their adherence to ACPE standards and objectives simply by using this book. A companion website for students and instructors further enhance the didactic content for students by including practice questions and answers and videos that feature difficult processes and procedures. Essential resources for instructors are also available and include chapter PowerPoint slides and full-color images. Full of practical examples and case studies for experiential learning, Pharmaceutics enables students to gain the scientific foundation to understand drug physicochemical properties, practical aspects of dosage forms and drug delivery systems, and the biological applications of drug administration.
Decision-Making for Supply Chain Integration
Effective supply chain integration, and the tight co-ordination it creates, is an essential pre-requisite for successful supply chain management. Decision-Making for Supply Chain Integration is a practical reference on recent research in the area of supply chain integration focusing on distributed decision-making problems. Recent applications of various decision-making tools for integrating supply chains are covered including chapters focusing on: Supplier selection, pricing strategy and inventory decisions in multi-level supply chains, RFID-enabled distributed decision-making, Operational risk issues and time-critical decision-making for sensitive logistics nodes, Modelling end to end processes to improve supply chain integration, and Integrated systems to improve service delivery and optimize resource use.Decision-Making for Supply Chain Integration provides an insight into the tools and methodologies of this field with support from real-life case studies demonstrating successful application of various decision-making techniques. By covering such a range of topics in this way, Decision-Making for Supply Chain Integration is a useful reference for researchers looking to develop their knowledge or find potential new avenues of research.
Luminescence Dating in Archaeology, Anthropology and Geoarchaeology
The field of Luminescence Dating has reached a level of maturity. Both research and applications from all fields of archaeological science, from archaeological materials to anthropology and geoarchaeology, now routinely employ luminescence dating. The advent of optically stimulated luminescence (OSL) techniques and the potential for exploring a spectrum of grain aliquots enhanced the applicability, accuracy and the precision of luminescence dating. The present contribution reviews the physical basis, mechanisms and methodological aspects of luminescence dating; discusses advances in instrumentations and facilities, improvements in analytical procedures, and statistical treatment of data along with some examples of applications across continents, covering all periods (Middle Palaeolithic to Medieval) and both Old and New World archaeology. They also include interdisciplinary applications that contribute to palaeo-landscape reconstruction.
Thứ Năm, 5 tháng 2, 2015
Integrating Renewable, Distributed and Efficient Energy
The creation of a flexible, efficient, digitized, dependable and resilient power grid may well be the best route to increasing energy efficiency & security, as well as boosting the potential of renewable & distributed power sources. However, there is still much confusion about the nature of the Smart Grid: What is it? What work needs to be accomplished in order to make it a reality? How will it benefit the drive to diversify energy resources? This book covers Smart Grids from A-Z, providing a complete treatment of the topic, covering both policy and technology, explaining the most recent innovations supporting its development, and clarifying how the Smart Grid can support the integration of Renewable Energy resources. Among the most important topics included are smart metering, renewable energy storage, plug-in hybrids, flexible demand response, strategies for offsetting intermittency issues, micro-grids for off-grid communities, and specific in-depth coverage of wind and solar power integration. The content draws lessons from an international panel of contributors, whose diverse experiences implementing smart grids will help to provide templates for success. If we intend to undertake a meaningful overhaul of the way the world uses energy resources, we ignore grid management issues at our peril. Ultimately, this important book examines what the integration challenges are, what technology and policy needs to be in place in order to support uptake, and what The Smart Grid can do to enable solutions. Provides critical information on the technological, design and policy issues that must be taken into account to ensure that the smart grid is implemented successfully Demonstrates how smart grids can help utilities adhere to increased renewable portfolio standards Provides examples of successful microgrid/smart metering projects from around the world that can act as templates for developers, operators and investors embarking upon similar projects.
Linear and Geometric Algebra
This textbook for the first undergraduate linear algebra course presents a unified treatment of linear algebra and geometric algebra, while covering most of the usual linear algebra topics. Geometric algebra is an extension of linear algebra. It enhances the treatment of many linear algebra topics. And geometric algebra does much more. Geometric algebra and its extension to geometric calculus unify, simplify, and generalize vast areas of mathematics that involve geometric ideas. They provide a unified mathematical language for many areas of physics, computer science, and other fields. The book can be used for self study by those comfortable with the theorem/proof style of a mathematics text. This is a second printing, corrected and slightly revised. Visit the book’s web site for more information: http: //faculty.luther.edu/ macdonal/laga I commend Alan Macdonald for his excellent book! His exposition is clean and spare. He has done a fine job of engineering a gradual transition from standard views of linear algebra to the perspective of geometric algebra. The book is sufficiently conventional to be adopted as a textbook by an adventurous teacher without getting flack from colleagues. Yet it leads to gems of geometric algebra that are likely to delight thoughtful students and surprise even the most experienced instructors. — David Hestenes, Distinguished Research Professor, Arizona State University
Thứ Ba, 3 tháng 2, 2015
The Noble Gases as Geochemical Tracers
The twelve chapters of this volume aim to provide a complete manual for using noble gases in terrestrial geochemistry, covering applications which range from high temperature processes deep in the Earths interior to tracing climatic variations using noble gases trapped in ice cores, groundwaters and modern sediments. Other chapters cover noble gases in crustal (aqueous, CO2 and hydrocarbon) fluids and laboratory techniques for determining noble gas solubilities and diffusivities under geologically relevant conditions. Each chapter deals with the fundamentals of the analysis and interpretation of the data, detailing sampling and sampling strategies, techniques for analysis, sources of error and their estimation, including data treatment and data interpretation using recent case studies.
Thứ Hai, 2 tháng 2, 2015
International Crime and Justice
International crime and justice is an emerging field that covers international and transnational crimes that have not been the focus of mainstream criminology or criminal justice. This book examines the field from a global perspective. It provides an introduction to the nature of international and transnational crimes and the theoretical perspectives that assist in understanding the relationship between social change and the waxing and waning of the crime opportunities resulting from globalization, migration, and culture conflicts. Written by a team of world experts, it examines the central role of victim rights in the development of legal frameworks for the prevention and control of transnational and international crimes. It also discusses the challenges to delivering justice and obtaining international cooperation in efforts to deter, detect, and respond to these crimes. This book is arranged in nine parts covering the subject matter of international criminal justice. Each of the short chapters provides readers with an understanding of the main concepts relevant to the topic and sensitizes them to the complex nature of the problems.
Chủ Nhật, 1 tháng 2, 2015
Physiology and Physiopathology of Adipose Tissue
The scientific advances in the physiology and pathophysiology of adipose tissue over the last two decades have been considerable. Today, the cellular and molecular mechanisms of adipogenesis are well known. In addition, adipose tissue is now recognized as a real endocrine organ that produces hormones such as the leptin acting to regulate food intake and energy balance in the central nervous system, a finding that has completely revolutionized the paradigm of energy homeostasis. Other adipokines have now been described and these molecules are taking on increasing importance in physiology and pathophysiology. Moreover, numerous works have shown that in obesity, but also in cases of lipodystophy, adipose tissue was the site of a local low-grade inflammation that involves immune cells such as macrophages and certain populations of lymphocytes. This new information is an important step in the pathophysiology of both obesity and related metabolic and cardiovascular complications. Finally, it is a unique and original work focusing on adipose tissue, covering biology and pathology by investigating aspects of molecular and cellular biology, general, metabolic, genetic and genomic biochemistry.
Thứ Năm, 29 tháng 1, 2015
Business Ratios and Formulas
Required reading for anyone starting, running, or growing a business, Business Ratios and Formulas, Second Edition puts answers at the fingertips of business managers, with nearly 250 operational criteria and clear, easy-to-understand explanations that can be used right away. The Second Edition includes approximately fifty new ratios and formulas, as well as new chapters covering ratios and formulas for e-commerce and human resources.
Thứ Tư, 28 tháng 1, 2015
Multi-Step Enzyme Catalysis
The first comprehensive coverage of this unique and interdisciplinary field provides a complete overview, covering such topics as chemoenzymatic synthesis, microbial production of DNA building blocks, asymmetric transformations by coupled enzymes and much more. By combining enzymatic and synthetic organic steps, the use of multi-enzyme complexes and other techniques opens the door to reactions hitherto unknown, making this monograph of great interest to biochemists, organic chemists, and chemists working with/on organometallics, as well as catalytic chemists, biotechnologists, and those working in the pharmaceutical and fine chemical industries.
Best Practice in Professional Supervision
Best Practice in Professional Supervision is an authoritative guide to being an excellent supervisor, covering the role, functions and dispositions involved. The authors consider basic skills, the practicalities of forming and maintaining the supervision relationship, and the organisational context and culture of supervision. The book offers practical examples and a model of supervision which draws together ideas from adult learning theory and reflective practice. Viewing supervision as a place for learning, this guide considers how supervision can assist practitioners to develop professional resilience and manage the stresses of complex work environments. It also includes specific chapters on supervision of clinical student placements and in child protection settings. This book covers a range of professions including social care, nursing, counselling, social work and allied health professions, and is an essential guide for all those in these and related professions undertaking supervision or supervision training.
Vietnam Studies
The United States Army has met an unusually complex challenge in Southeast Asia. In conjunction with the other services, the Army has fought in support of a national policy of assisting an emerging nation to develop governmental processes of its own choosing, free of outside coercion. In addition to the usual problems of waging armed conflict, the assignment in Southeast Asia has required superimposing the immensely sophisticated tasks of a modern army upon an underdeveloped environment and adapting them to demands covering a wide spectrum. These involved helping to fulfill the basic needs of an agrarian population, dealing with the frustrations of antiguerrilla operations, and conducting conventional campaigns against well-trained and determined regular units.