Atoms, Molecules and Photons

Atoms, Molecules and Photons

This introduction to Atomic and Molecular Physics explains how our present model of atoms and molecules has been developed over the last two centuries, both by many experimental discoveries and, from the theoretical side, by the introduction of quantum physics to the adequate description of micro-particles. It illustrates the wave model of particles by many examples and shows the limits of classical description. The interaction of electromagnetic radiation with atoms and molecules and its potential for spectroscopy is outlined in great detail and, in particular, lasers as modern spectroscopic tools are discussed thoroughly. Many examples and problems with solutions are offered to encourage readers to actively participate in applying and adapting the fundamental physics presented in this textbook to specific situations.

Atoms, Molecules and Photons

Gene Therapy

Gene Therapy

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. Volume 40, GeneTherapy, features important new research on gene transfers and therapy in the herpes simplex virus, anti-tumor immunity, steroid receptors, cystic fibroses, and more.

Gene Therapy

An Introduction to Markov State Models and Their Application to Long Timescale Molecular Simulation

An Introduction to Markov State Models and Their Application to Long Timescale Molecular Simulation

The aim of this book volume is to explain the importance of Markov state models to molecular simulation, how they work, and how they can be applied to a range of problems.

An Introduction to Markov State Models and Their Application to Long Timescale Molecular Simulation

Clusters in Nuclei, Volume 3

Clusters in Nuclei, Volume 3

Following the pioneering discovery of alpha clustering and of molecular resonances, the field of nuclear clustering is today one of those domains of heavy-ion nuclear physics that faces the greatest challenges, yet also contains the greatest opportunities. After many summer schools and workshops, in particular over the last decade, the community of nuclear molecular physicists has decided to collaborate in producing a comprehensive collection of lectures and tutorial reviews covering the field. This third volume follows the successful Lect. Notes Phys. 818 (Vol. 1) and 848 (Vol. 2), and comprises six extensive lectures covering the following topics:

Clusters in Nuclei, Volume 3

The Mystery of Glaucoma

The Mystery of Glaucoma

Since long ago scientists have been trying hard to show up the core of glaucoma. To its understanding we needed to penetrate gradually to its molecular level. The newest pieces of knowledge about the molecular biology of glaucoma are presented in the first section. The second section deals with the clinical problems of glaucoma. Ophthalmologists and other medical staff may find here more important understandings for doing their work. What would our investigation be for, if not owing to the peoples benefit? The third section is full of new perspectives on glaucoma. After all, everybody believes and relies more or less on bits of hopes of a better future. Just let us engage in the mystery of glaucoma, to learn how to cure it even to prevent suffering from it. Each information in this book is an item of great importance as a precious stone behind which genuine, through and honest piece of work should be observed.

The Mystery of Glaucoma

Vortex, Molecular Spin and Nanovorticity

Vortex, Molecular Spin and Nanovorticity

The subject of this book is the physics of vortices. A detailed analysis of the dynamics of vortices will be presented. The important topics of vorticity and molecular spin will be dealt with, including the electromagnetic analogy and quantization in superfluids. The effect of molecular spin on the dynamics of molecular nano-confined fluids using the extended Navier-Stokes equations will also be covered especially important to the theory and applicability of nanofluidics and associated devices. The nanoscale boundary layer and nanoscale vortex core are regions of intense vorticity (molecular spin). It will be shown, based on molecular kinetic theory and thermodynamics, that the macroscopic (solid body) rotation must be accompanied by internal rotation of the molecules. Electric polarization of the internal molecular rotations about the local rotation axis the Barnett effect occurs. In such a spin aligned system, major changes in the physical properties of the fluid result.

Vortex, Molecular Spin and Nanovorticity

Computational Organometallic Chemistry

Computational Organometallic Chemistry

This work provides a how-to approach to the fundamentals, methodologies and dynamics of computational organometallic chemistry, including classical and molecular mechanics (MM), quantum mechanics (QM), and hybrid MM/QM techniques. It demonstrates applications in actinide chemistry, catalysis, main group chemistry, medicine, and organic synthesis.

Computational Organometallic Chemistry

Topics in Stereochemistry, Volume 23

Topics in Stereochemistry, Volume 23

Topics in Stereochemistry covers the fundamental principles of physical chemistry and molecular physics while dealing with certain stereochemical aspects of organic chemistry and biochemistry.

Topics in Stereochemistry, Volume 23

Biology of Stem Cells and the Molecular Basis of the Stem State

Biology of Stem Cells and the Molecular Basis of the Stem State

Biology of Stem Cells and the Molecular Basis of the Stem State concentrates upon adult stem cells, particularly on mesenchymal cell populations, which is the authors area of expertise. The text offers the reader a detailed description of the emergence of stem cell research and the dogmas that were created during the first decades of analysis of stem cell properties, particularly those of hemopoietic stem cells. Biology of Stem Cells and the Molecular Basis of the Stem State also introduces the reader to the commonly accepted notions regarding stem cell biology, with an emphasis on an alternative view of stemness, i.e. the stem state. In keeping with the popularity of this topic, Biology of Stem Cells and the Molecular Basis of the Stem State addresses the major controversies and points of dispute, among researchers in the stem cell field. Overall, Biology of Stem Cells and the Molecular Basis of the Stem State presents a well-rounded dialogue about stem cells as it not only concentrates upon the biological elements of stem cell, but also addresses the controversy and hype currently enveloping this popular subject.

Biology of Stem Cells and the Molecular Basis of the Stem State

Semiconductor Physics

Semiconductor Physics

This well-established monograph, updated and now in its ninth edition, deals mainly with electron transport in, and optical properties of semiconductors. It includes lasers, e.g. the quantum cascade laser, quantum processes such as the quantum Hall effect, quantum dots, fullerenes, carbon nanotubes, molecular electronics, the nitrides, and many other recent discoveries in the field. New diagrams and tables provide a comprehensive source of materials data. Selected problems help readers to consolidate their knowledge and invite teachers to use this text for graduate courses on semiconductor physics, solid state physics, and physical electronics.

Semiconductor Physics

Phospholipases in Plant Signaling

Phospholipases in Plant Signaling

This volume focuses on recent advances in the biochemical and molecular analysis of different families of phospholipases in plants and their roles in signaling plant growth, development and responses to abiotic and biotic cues.

Phospholipases in Plant Signaling

Skeletal Development and Repair

Skeletal Development and Repair

Skeletal Development and Repair: Methods and Protocols is a compilation of a variety of skeletal research protocols utilizing the laboratory mouse as the platform for surgical manipulation and/or transplantation as well as the source of tissues and cells for in vitro culture and analyses. Chapters are written by experts in the field and cover topics including surgical, transplantation and organ culture methods that permit analyses of skeletal tissues undergoing repair in vivo and permits analyses of cellular interactions ex vivo, histological and molecular techniques developed to study gene and protein expression in whole embryos, skeletal tissues and tissue sections and in vitro primary cell culture protocols designed to assay gene function in specific cell populations. Written in the successful Methods in Molecular Biology series format chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls.

Skeletal Development and Repair

Auditory Trauma, Protection and Repair

Auditory Trauma, Protection and Repair

The past decade has brought great advances in our understanding of the mechanisms underlying auditory pathologies. Molecular biology and genetics have primarily contributed to this enhanced understanding, which in turn has driven the design of novel rational therapeutic interventions. This volume presents recent developments in research and their potential translation to the clinical setting. The volume addresses the major entities of peripheral auditory trauma, discusses the underlying mechanisms, the central nervous system consequences, protective interventions and finally explores the possibilities to restore cochlear morphology and function.

Auditory Trauma, Protection and Repair

International Review of Cell and Molecular Biology

International Review of Cell and Molecular Biology

International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology–both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth.

International Review of Cell and Molecular Biology

Molecular Assembly of Biomimetic Systems

Molecular Assembly of Biomimetic Systems

This handy reference details state-of-the-art preparation of molecular assemblies of biotechnologically relevant biomimetic systems (artificial proteins, peptides, molecular motors, photosensitive systems) with an emphasis on biomimetic membranes, capsules, and interfaces. Medical applications such as drug release, gene therapy, and tissue engineering as well as biosensing, biocatalysis, and energy storage are highlighted.

Molecular Assembly of Biomimetic Systems