Yen and Jaffes Reproductive Endocrinology

Yen and Jaffes Reproductive Endocrinology

Thoroughly revised and now enhanced with color artwork, the new edition of this premier reference continues to offer the latest information on the diagnosis and management of reproductive endocrine disorders. National and international leaders from the field of reproductive endocrinology-including 30 new authors-equip you with coverage that encompasses the full spectrum of reproductive pathophysiology and disorders, from pregnancy and birth to reproductive aging. Full-color illustrations and new drawings provide a real-life depiction of basic cell structures and endocrine responses for a better understanding of the material, while new chapters explore the issues shaping todays practice. As an Expert Consult title, it includes convenient online access to the complete text of the book-fully searchable-along with all of the images, and references linked to Medline at www.expertconsult.com.

Yen and Jaffes Reproductive Endocrinology

The Cloning Sourcebook

The Cloning Sourcebook

Animal cloning has developed quickly since the birth of Dolly the sheep. Yet many of the first questions to be raised still need to be answered. What do Dolly and her fellow mouse, cow, pig, goat and monkey clones mean for science? And for society? Why do so many people respond so fearfully to cloning? What are the ethical issues raised by cloning animals, and in the future, humans? How are the makers of public policy coping with the stunning fact that an entire animal can be reconstructed from a single adult cell? And that humans might well be next? The Cloning Source Book addresses all of these questions in a way that is unique in the cloning literature, by grounding what is effectively an interdisciplinary conversation in solid science. In the first section of the book, the key scientists responsible for the early and crucial developments in cloning speak to us directly, and other scientists evaluate and comment on these developments. The second section explores the context of cloning and includes sociological, mythological, and historical perspectives on science, ethics, and policy. The authors also examine the media’s treatment of the Dolly story and its aftermath, both in the United States and in Britain. The third section, on ethics, contains a broad range of papers written by some of the major commentators in the field. The fourth section addresses legal and policy issues. It features individual and collective contributions by those who have actually shaped public policy on reproductive cloning, therapeutic cloning, and similarly contentious bioethical issues in the United States, Britain, and the European Union. Animal cloning continues for agricultural and medicinal purposes, the latter in combination with transgenics. Human cloning for therapeutic purposes has recently been made legal in Britain. The goal is to produce an early embryo and then derive stem cells that are immunologically matched to the donor. Two human reproductive cloning projects have been announced, and there are almost certainly others about which we know nothing. Sooner or later a cloned human will be born. Many lessons can be learned from the cloning experience. Most importantly, there needs to be a public conversation about the permissible uses of new and morally murky technologies. Scientists, journalists, ethicists and policy makers all have roles to play, but cutting-edge science is everybody’s business. The Cloning Sourcebook provides the tools required for us to participate in shaping our own futures.

The Cloning Sourcebook

An Introduction to Toxicology

An Introduction to Toxicology

This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. An Introduction to Toxicology is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that unpack the concepts being discussed in the text.

An Introduction to Toxicology

Pediatric Urology - Second Edition

Pediatric Urology - Second Edition

Pediatric Urology is an up-to-date, clinical reference that provides detailed descriptions of the best approaches for the functional, biological, and morphological aspects of the urinary tract before and after birth. John G. Gearhart, Richard C. Rink, and Pierre D. E. Mouriquand cover all areas of the field, including pediatric surgery, radiology, nephrology, endocrinology, biochemistry, and obstetrics. Access the latest research through new chapters on tissue engineering, acute scrotum, and more. The appealing new full-color design, streamlined approach, and online access at expertconsult.com make this an invaluable resource to pediatric urologists, pediatric surgeons, residents and fellows worldwide.

Pediatric Urology - Second Edition

Witchcraft and Colonial Rule in Kenya, 1900-1955

Witchcraft and Colonial Rule in Kenya, 1900-1955

Focusing on colonial Kenya, this book shows how conflicts between state authorities and Africans over witchcraft-related crimes provided an important space in which the meanings of justice, law, and order in the empire were debated. Katherine Luongo discusses the emergence of imperial networks of knowledge about witchcraft. She then demonstrates how colonial concerns about witchcraft produced an elaborate body of jurisprudence about capital crimes. The book analyzes the legal wrangling that produced the Witchcraft Ordinances in the 1910s, the birth of an anthro-administrative complex surrounding witchcraft in the 1920s, the hotly contested Wakamba Witch Trials of the 1930s, the explosive growth of legal opinion on witch-murder in the 1940s, and the unprecedented state-sponsored cleansings of witches and Mau Mau adherents during the 1950s. A work of anthropological history, this book develops an ethnography of Kamba witchcraft or uoi.

Witchcraft and Colonial Rule in Kenya, 1900-1955

Key Chiral Auxiliary Applications, Second Edition

Key Chiral Auxiliary Applications, Second Edition

Asymmeric synthesis is extremely important for many applications, especially in industrial chemistry. When a reaction forms a chiral molecule, the two possible enantiomeric products can have very different properties; one may be a beneficial drug and the other may be toxic. It is therefore very important to be able to make a pure enantiomer. For example the drug thalidimide was used in the 1950s by women to reduce the discomfort of pregnancy; unknown at the time, it was a mixture of enantiomers of the same molecule. One enantiomer was therapeutic, the other was later found to be toxic, but had already resulted in many cases of birth defects, particularly in Japan and Europe. Chiral molecules are also involved in dyes and pigments, fragrances, flavors and many other commercial applications. One alternative to using a chiral auxiliary to make a pure enantiomer is to make both enantiomers and then purify out the desired one but this method is wasteful in terms of chemicals used, expensive and time consuming.

Key Chiral Auxiliary Applications, Second Edition

The Real Rio D Aquila

The Real Rio D Aquila

Italian by birth, this street urchin lived a life of extreme poverty until he escaped to Brazilwhere he cast off his roots, took a new name and pulled himself up from the streets.

The Real Rio D Aquila

Then I Met My Sister

Then I Met My Sister

It’s not exactly easy living in a shrine to your dead sister. Since birth, I’ve known that everyone loved Shannon. She was perfect–beautiful, smart, talented. And me? Not so much. My parents always expected me to live up to her greatness. But I could never measure up to her, so why even try?

Then I Met My Sister

Major Tudor Authors

Major Tudor Authors

The Tudor era (1485-1603) was one of the most culturally significant periods in history. Under three generations of Tudor rulers, the era witnessed the advent of humanism, the birth of the Reformation, and the rise of the British Empire. The literature of the period is marked by complexity of thought and form and reflects the political, religious, and cultural changes of the era. Within slightly more than a century, literature in English evolved from late medieval, mostly in Scotland, to high renaissance, mostly in England. Classical myth merged with Christian teaching, continental thinkers influenced English culture, and developments in science fostered the growth of early modern civilization. This reference book is a guide to the rich and diverse literature of Tudor England. Included are entries for nearly 100 people who wrote between 1485 and 1603. The entries are written by expert contributors and are arranged alphabetically to facilitate use. Some of the authors profiled are major canonical figures, such as Shakespeare, Spenser, and Donne. But the volume also includes a significant number of entries for women writers, whose work has been unjustly disregarded until recent years. While most of the authors were from England, the volume contains entries on figures such as Erasmus, who, though born in another country, wrote important works in England, and on writers such as Machiavelli, Calvin, Ariosto, and Tasso, whose works were almost immediately adopted, translated, or otherwise made part of Tudor culture. Each entry provides a brief biography, which is followed by a discussion of major works and themes, a review of the author’s critical reception, and a bibliography of primary and secondary sources.

Major Tudor Authors

The Plan

The Plan

Cindy is heartbroken. The love of her young life, the person she has idolised since birth, has died. Cindy loved her sister more than life itself, she was her whole world, but then she committed suicide and Cindy wants to know why.

The Plan

An Osteopathic Approach to Children

An Osteopathic Approach to Children

This evidence-based, fully referenced text offers a wealth of information on the use of osteopathic techniques for pediatric disorders — from newborns to adolescents. It discusses normal development, physiology, and anatomy of the systems, and it explores conditions and diseases of childhood as well as the rationale for osteopathic treatment. Practical and comprehensive, it offers an osteopathic approach to understanding the development of the cranium; the interrelatedness of posture, movement, and cognition; and the process of labor and birth.

An Osteopathic Approach to Children

Chronology of Organized Crime Worldwide, 6000 B.C.E. to 2010

Chronology of Organized Crime Worldwide, 6000 B.C.E. to 2010

Organized crime has played a significant social role in cultures all over the world. This is the first book to establish a timeline of global organized criminal activity, which spans eight millennia. Entries are arranged chronologically and represent many facets of the criminal underground, including the birth of major players in crime as well as law enforcement officials, the discovery or invention of drugs and weapons, the creation of law enforcement agencies, and the passage of statutes relevant to the control of criminal activity. A broadly useful examination of organized crime, this book encompasses all nations, races, religions and political philosophies.

Chronology of Organized Crime Worldwide, 6000 B.C.E. to 2010

The Sacrament of Language

The Sacrament of Language

This book is a continuation of Giorgio Agamben’s investigation of political theory, which began with the highly influential volume Homo Sacer: Sovereign Power and Bare Life. Having already traced the roots of the idea of sovereignty, sacredness, and economy, he now turns to a perhaps unlikely topic: the concept of the oath. Following the Italian scholar Paolo Prodi, Agamben sees the oath as foundational for Western politics and undertakes an exploration of the roots of the phenomenon of the oath in human experience. He rejects the common idea that the oath finds its origin in religion, arguing instead that the oath points toward a particular response to the experience of language, a response that gave birth to both religion and law as we now know them. This book is important not only for readers of Agamben or of continental philosophy more broadly, but for anyone interested in questions relating to the relationships among religion, law, and language.

The Sacrament of Language

Big Data Now: 2012 Edition

Big Data Now: 2012 Edition

The Big Data Now anthology is relevant to anyone who creates, collects or relies upon data. It’s not just a technical book or just a , guide. Data is ubiquitous and it doesn’t pay much attention to borders, so we’ve calibrated our coverage to follow it wherever it goes.,

In the first edition of Big Data Now, the O’Reilly team tracked the birth and early development of data tools and data science. Now, with this second edition, we’re seeing what happens when big data grows up: how it’s being applied, where it’s playing a role, and the consequences – good and bad alike – of data’s ascendance.

Big Data Now: 2012 Edition